Question

A 48-year-old woman presents with low mood, early morning waking, weight loss and suicidal thoughts. There is no psychosis. According to NICE, what is an appropriate first-line pharmacological option for more severe depression in primary care?

Accepted Answer

Selective serotonin reuptake inhibitor such as Sertraline

Answer

Tricyclic antidepressant such as Amitriptyline as first-line

Answer

Monoamine oxidase inhibitor as first-line

Answer

Benzodiazepines alone

Answer

Antipsychotic monotherapy

Practice question

A 48-year-old woman presents with low mood, early morning waking, weight loss and suicidal thoughts. There is no psychosis. According to NICE, what is an appropriate first-line pharmacological option for more severe depression in primary care?