A 64-year-old man presents with vomiting and reduced urine output after starting high-dose Ibuprofen for back pain. Urea and creatinine are significan...

Question

A 64-year-old man presents with vomiting and reduced urine output after starting high-dose Ibuprofen for back pain. Urea and creatinine are significantly raised from baseline, with hyperkalaemia and metabolic acidosis. What is the most appropriate initial step in management?

Accepted Answer

Stop NSAIDs and assess volume status, giving intravenous fluids as indicated

Answer

Start long-term dialysis immediately

Answer

Give oral sodium bicarbonate

Answer

Start high-dose ACE inhibitor to protect kidneys

Answer

No action required as this is expected with NSAIDs

uk-plab-1 MCQ (SBA): Acute kidney injury

A 64-year-old man presents with vomiting and reduced urine output after starting high-dose Ibuprofen for back pain. Urea and creatinine are significantly raised from baseline, with hyperkalaemia and metabolic acidosis. What is the most appropriate initial step in management?