A 34-year-old woman presents with chronic diarrhoea, weight loss and iron-deficiency anaemia. She also reports intermittent abdominal bloating. What i...

Question

A 34-year-old woman presents with chronic diarrhoea, weight loss and iron-deficiency anaemia. She also reports intermittent abdominal bloating. What is the most appropriate initial investigation to confirm suspected coeliac disease?

Accepted Answer

Serum tissue transglutaminase IgA antibodies with total IgA

Answer

Immediate gluten-free diet without testing

Answer

Colonoscopy with random biopsies only

Answer

Hydrogen breath test for lactose intolerance

Answer

Plain abdominal X-ray

uk-plab-1 MCQ (SBA): Coeliac disease – diagnosis

A 34-year-old woman presents with chronic diarrhoea, weight loss and iron-deficiency anaemia. She also reports intermittent abdominal bloating. What is the most appropriate initial investigation to confirm suspected coeliac disease?