HardCardiovascularChronic heart failure with reduced ejection fractionuk-plab-1
A 72-year-old man with ischaemic cardiomyopathy (left ventricular ejection fraction 30%) presents with exertional dyspnoea and ankle swelling. He is euvolaemic today after recent diuretic titration. What is the most appropriate combination of core disease-modifying drugs for his chronic heart failure with reduced ejection fraction, assuming no contraindications?