A 78-year-old woman has non-valvular atrial fibrillation with a CHA2DS2-VASc score of 4. She has no major contraindications to anticoagulation. What is the most appropriate long-term stroke prevention strategy?AStart a direct oral anticoagulant such as ApixabanBStart Aspirin 75 mg once dailyCNo antithrombotic therapy is requiredDStart dual antiplatelet therapy with Aspirin and ClopidogrelEStart low molecular weight heparin indefinitelyCheck my answer