A 60-year-old man presents with bone pain, recurrent chest infections and fatigue. Blood tests show normocytic anaemia, raised ESR and corrected calci...

Question

A 60-year-old man presents with bone pain, recurrent chest infections and fatigue. Blood tests show normocytic anaemia, raised ESR and corrected calcium of 2.85 mmol/L. Serum creatinine is 180 µmol/L. What is the most appropriate initial investigation to confirm the suspected diagnosis?

Accepted Answer

Serum protein electrophoresis and serum free light chains

Answer

Bone marrow biopsy only

Answer

Whole-body MRI scan only

Answer

Serum ferritin and transferrin saturation

Answer

D-dimer test

uk-plab-1 MCQ (SBA): Multiple myeloma

A 60-year-old man presents with bone pain, recurrent chest infections and fatigue. Blood tests show normocytic anaemia, raised ESR and corrected calcium of 2.85 mmol/L. Serum creatinine is 180 µmol/L. What is the most appropriate initial investigation to confirm the suspected diagnosis?