A 29-year-old woman has chronic tiredness and iron-deficiency anaemia. Coeliac serology shows positive tissue transglutaminase (tTG) IgA antibodies. W...

Question

A 29-year-old woman has chronic tiredness and iron-deficiency anaemia. Coeliac serology shows positive tissue transglutaminase (tTG) IgA antibodies. What is the most appropriate next step?

Accepted Answer

Refer for duodenal biopsy while she remains on a gluten-containing diet

Answer

Start a gluten-free diet immediately without further investigation

Answer

Repeat serology after starting iron therapy

Answer

Label her as having non-coeliac gluten sensitivity

Answer

Discharge with reassurance

uk-plab-1 MCQ (SBA): Coeliac disease diagnosis pathway

A 29-year-old woman has chronic tiredness and iron-deficiency anaemia. Coeliac serology shows positive tissue transglutaminase (tTG) IgA antibodies. What is the most appropriate next step?