ModerateCardiovascularChronic heart failure with reduced ejection fractionuk-plab-1
A 68-year-old man with long-standing hypertension and ischaemic heart disease presents with exertional dyspnoea and ankle swelling. Echocardiography shows a left ventricular ejection fraction of 30%. He is already on an ACE inhibitor and a beta-blocker at target dose. According to NICE guidance, which additional drug class should be considered to reduce hospitalisation and mortality?