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EasyCardiovascularHypertension initial drug choiceuk-plab-1

A 49-year-old white British man is newly diagnosed with stage 2 primary hypertension (clinic BP 162/96 mmHg on repeated readings and elevated ambulatory readings). He has no diabetes, kidney disease or cardiovascular disease. According to NICE guidance, what is the most appropriate first-line antihypertensive agent?

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