A 55 year old man with known rheumatoid arthritis has persistent active disease despite optimal Methotrexate. According to NICE guidance, which of the...

Question

A 55 year old man with known rheumatoid arthritis has persistent active disease despite optimal Methotrexate. According to NICE guidance, which of the following is the most appropriate next step in disease modifying therapy if criteria are met?

Accepted Answer

Consider adding a biologic DMARD such as a TNF inhibitor

Answer

Add low dose Prednisolone alone

Answer

Switch to NSAID monotherapy

Answer

Stop all DMARDs and observe

Answer

Use opioid analgesia only

uk-plab-1 MCQ (SBA): Escalation of rheumatoid arthritis therapy

A 55 year old man with known rheumatoid arthritis has persistent active disease despite optimal Methotrexate. According to NICE guidance, which of the following is the most appropriate next step in disease modifying therapy if criteria are met?