Question

A 72 year old woman on long term Warfarin for atrial fibrillation presents with sudden onset severe headache, vomiting and reduced consciousness. CT head shows an intracerebral haemorrhage. Her INR is 4.5. According to BNF and emergency guidance, what is the most appropriate immediate step regarding her anticoagulation?

Accepted Answer

Stop Warfarin and give intravenous Vitamin K plus Prothrombin complex concentrate

Answer

Continue Warfarin at the same dose

Answer

Stop Warfarin and give oral Vitamin K only

Answer

Reduce Warfarin dose but continue therapy

Answer

Switch immediately to a direct oral anticoagulant

Practice question