A 62-year-old woman presents with fatigue and pruritus. Blood tests show Hb 128 g/L, WCC 6 ×10⁹/L, platelets 320 ×10⁹/L, ALP markedly raised, and bili...

Question

A 62-year-old woman presents with fatigue and pruritus. Blood tests show Hb 128 g/L, WCC 6 ×10⁹/L, platelets 320 ×10⁹/L, ALP markedly raised, and bilirubin mildly elevated. Anti-mitochondrial antibodies are strongly positive. What is the most likely diagnosis?

Accepted Answer

Primary biliary cholangitis

Answer

Primary sclerosing cholangitis

Answer

Autoimmune hepatitis

Answer

Alcoholic hepatitis

Answer

Gallstone obstruction

uk-plab-1 MCQ (SBA): Primary biliary cholangitis – diagnosis

A 62-year-old woman presents with fatigue and pruritus. Blood tests show Hb 128 g/L, WCC 6 ×10⁹/L, platelets 320 ×10⁹/L, ALP markedly raised, and bilirubin mildly elevated. Anti-mitochondrial antibodies are strongly positive. What is the most likely diagnosis?