Question

A 21-year-old man with sickle cell disease presents with severe generalised bone pain, fever, and tachycardia. Oxygen saturations are 93% on air, and chest X-ray is normal. What is the most appropriate immediate management?

Accepted Answer

Admit for oxygen, IV fluids, strong opioids, and treat any infection

Answer

High-dose NSAIDs alone at home

Answer

Start hydroxycarbamide immediately and discharge

Answer

Exchange transfusion in all cases

Answer

Observe without analgesia

Practice question

A 21-year-old man with sickle cell disease presents with severe generalised bone pain, fever, and tachycardia. Oxygen saturations are 93% on air, and chest X-ray is normal. What is the most appropriate immediate management?