Question

A 67-year-old woman on long-term Warfarin for atrial fibrillation presents with massive haematemesis and hypotension. Her INR is 6.5. What is the most appropriate immediate strategy to reverse anticoagulation?

Accepted Answer

Give intravenous Vitamin K and four-factor Prothrombin Complex Concentrate

Answer

Stop Warfarin only and observe

Answer

Give oral Vitamin K alone

Answer

Give fresh frozen plasma alone

Answer

Switch from Warfarin to a direct oral anticoagulant

Practice question

A 67-year-old woman on long-term Warfarin for atrial fibrillation presents with massive haematemesis and hypotension. Her INR is 6.5. What is the most appropriate immediate strategy to reverse anticoagulation?