A 63-year-old woman with a 35-year history of smoking and chronic cough presents with increasing dyspnoea on exertion. Spirometry shows FEV1 55 percen...

Question

A 63-year-old woman with a 35-year history of smoking and chronic cough presents with increasing dyspnoea on exertion. Spirometry shows FEV1 55 percent predicted and FEV1/FVC 0.55 post-bronchodilator. She is already on a long-acting muscarinic antagonist. According to Canadian COPD pharmacotherapy guidance, which next step is most appropriate to reduce exacerbations?

Accepted Answer

Add a long-acting beta agonist to create dual bronchodilation

Answer

Add a short-acting salbutamol inhaler only

Answer

Switch to inhaled corticosteroid monotherapy

Answer

Start chronic oral prednisone 5 mg daily

Answer

Add long-term macrolide therapy immediately

ca-mccqe1 MCQ (SBA): Chronic obstructive pulmonary disease pharmacotherapy