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MediumPsychiatryMajor depressive disorderca-mccqe1ca-ccfpca-rcpsc-im

A 38-year-old woman presents with low mood, anhedonia, poor sleep and impaired functioning for 8 weeks. There is no suicidality, psychosis or bipolar history. She has not previously received treatment. According to the 2023 CANMAT guidelines, what is the most appropriate first-line treatment?

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