Question

A 65-year-old man with COPD (FEV1 45% predicted) has frequent exacerbations despite long-acting bronchodilator therapy. According to CTS COPD guidelines, which additional intervention has strong evidence to reduce future exacerbations and mortality in selected patients with chronic bronchitis phenotype?

Accepted Answer

Addition of inhaled corticosteroid to LABA/LAMA in patients with eosinophilic phenotype or frequent exacerbations

Answer

Long-term macrolide monotherapy in all patients

Answer

Chronic oral corticosteroids

Answer

Roflumilast in patients with purely emphysematous phenotype

Answer

Stopping all inhaled therapy and using short-acting bronchodilators only

Practice question