Question

A 60-year-old man with known cirrhosis presents with new onset confusion, asterixis and disorientation. There is no focal neurological deficit. What is the most appropriate initial pharmacologic therapy?

Accepted Answer

Lactulose titrated to 2-3 soft stools per day

Answer

High-dose loop diuretics

Answer

Metronidazole only

Answer

Benzodiazepines to reduce agitation

Answer

Immediate liver transplant referral only

Practice question

A 60-year-old man with known cirrhosis presents with new onset confusion, asterixis and disorientation. There is no focal neurological deficit. What is the most appropriate initial pharmacologic therapy?