Question

A 49-year-old woman on thyroxine replacement for primary hypothyroidism has persisted fatigue. TSH is 8.0 mIU/L (reference 0.4-4.0) and free T₄ is at the lower end of normal. She is taking thyroxine 75 micrograms daily. What is the most appropriate management?

Accepted Answer

Increase thyroxine dose and repeat thyroid function tests in 6-8 weeks

Answer

Stop thyroxine and repeat tests in 3 months

Answer

Add liothyronine (T₃) immediately

Answer

No change; TSH of 8.0 mIU/L is acceptable

Answer

Start carbimazole

Practice question

A 49-year-old woman on thyroxine replacement for primary hypothyroidism has persisted fatigue. TSH is 8.0 mIU/L (reference 0.4-4.0) and free T₄ is at the lower end of normal. She is taking thyroxine 75 micrograms daily. What is the most appropriate management?