Question

A 52-year-old man with non-alcoholic fatty liver disease (NAFLD) confirmed on ultrasound and elevated ALT has no evidence of cirrhosis. He has BMI 33 kg/m², type 2 diabetes and hyperlipidaemia. What is the most important disease-modifying intervention to reduce his liver-related risk?

Accepted Answer

Achieve sustained weight loss of 7-10% of body weight through diet and exercise

Answer

Commence high-dose vitamin E supplements

Answer

Start long-term prophylactic antibiotics

Answer

Start corticosteroid therapy

Answer

Avoid all statins

Practice question

A 52-year-old man with non-alcoholic fatty liver disease (NAFLD) confirmed on ultrasound and elevated ALT has no evidence of cirrhosis. He has BMI 33 kg/m², type 2 diabetes and hyperlipidaemia. What is the most important disease-modifying intervention to reduce his liver-related risk?