A 48-year-old man with obesity (BMI 32 kg/m²) is newly diagnosed with type 2 diabetes after A1C 8.2 percent. His eGFR is 90 mL/min/1.73 m², and liver ...

Question

A 48-year-old man with obesity (BMI 32 kg/m²) is newly diagnosed with type 2 diabetes after A1C 8.2 percent. His eGFR is 90 mL/min/1.73 m², and liver enzymes are normal. He has implemented diet and exercise changes for 3 months with minimal improvement in fasting glucose. According to Diabetes Canada, which pharmacologic agent should be initiated first line in most people in this situation?

Accepted Answer

Metformin

Answer

Basal insulin

Answer

Sulfonylurea (e.g., gliclazide)

Answer

SGLT2 inhibitor (e.g., empagliflozin)

Answer

DPP-4 inhibitor (e.g., sitagliptin)

ca-mccqe1 MCQ (SBA): Type 2 diabetes mellitus