Question

A 68-year-old woman with non-valvular atrial fibrillation, hypertension and type 2 diabetes has a CHA₂DS₂-VASc score of 4. Her creatinine clearance is 60 mL/min. She has no history of bleeding. What is the most appropriate stroke prevention strategy?

Accepted Answer

Full-dose direct oral anticoagulant therapy

Answer

No antithrombotic therapy is required

Answer

Low-dose aspirin alone

Answer

Therapeutic warfarin with target INR 1.5-2.0

Answer

Dual antiplatelet therapy with aspirin and clopidogrel

Practice question

A 68-year-old woman with non-valvular atrial fibrillation, hypertension and type 2 diabetes has a CHA₂DS₂-VASc score of 4. Her creatinine clearance is 60 mL/min. She has no history of bleeding. What is the most appropriate stroke prevention strategy?