Question

A 42-year-old woman presents with central obesity, hirsutism, acne and irregular menses. Examination shows purple abdominal striae and proximal myopathy. What is the most appropriate initial screening test for Cushing's syndrome?

Accepted Answer

Overnight 1 mg dexamethasone suppression test

Answer

Random serum cortisol

Answer

Short Synacthen test

Answer

24-hour urinary catecholamines

Answer

Fasting ACTH level alone

Practice question

A 42-year-old woman presents with central obesity, hirsutism, acne and irregular menses. Examination shows purple abdominal striae and proximal myopathy. What is the most appropriate initial screening test for Cushing's syndrome?