A 58-year-old man presents to a small rural emergency department 70 minutes after the sudden onset of severe central chest pain radiating to his left arm. ECG shows 3 mm ST elevation in leads II, III and aVF. The nearest PCI-capable centre is 250 km away and estimated transfer time is 3 hours. He has no contraindications to fibrinolysis. What is the most appropriate immediate reperfusion strategy?