A 50-year-old woman has 6 months of symmetrical pain and swelling in the MCP and PIP joints with morning stiffness of 90 minutes. Rheumatoid factor an...

Question

A 50-year-old woman has 6 months of symmetrical pain and swelling in the MCP and PIP joints with morning stiffness of 90 minutes. Rheumatoid factor and anti-CCP antibodies are positive. According to the Canadian Rheumatology Association living guidelines, which is the preferred initial disease-modifying therapy in the absence of contraindications?

Accepted Answer

Methotrexate monotherapy

Answer

Hydroxychloroquine monotherapy

Answer

Sulfasalazine monotherapy

Answer

Long-term low-dose oral prednisone only

Answer

Biologic agent as first-line monotherapy

ca-rcpsc-im MCQ (SBA): Rheumatoid arthritis