Question

A 48-year-old otherwise healthy man has repeated in-office blood pressures around 155/96 mmHg. Lifestyle modification has been initiated. He has no diabetes, chronic kidney disease, or cardiovascular disease. According to Hypertension Canada, what is the most appropriate first-line pharmacologic monotherapy?

Accepted Answer

Thiazide or thiazide-like diuretic (e.g., hydrochlorothiazide or chlorthalidone)

Answer

Non-selective beta-blocker (e.g., propranolol)

Answer

Direct renin inhibitor monotherapy

Answer

Alpha-1 blocker (e.g., doxazosin)

Answer

Long-acting loop diuretic (e.g., furosemide)

Practice question