Question

A 67-year-old man presents with night sweats, weight loss and painless cervical lymphadenopathy. Chest X-ray shows a widened mediastinum. What is the single most appropriate diagnostic test to establish the cause of his lymphadenopathy?

Accepted Answer

Excisional biopsy of an affected lymph node

Answer

Fine-needle aspiration cytology of a cervical node

Answer

Core needle biopsy of the largest node

Answer

Bone marrow biopsy

Answer

PET scan

Practice question

A 67-year-old man presents with night sweats, weight loss and painless cervical lymphadenopathy. Chest X-ray shows a widened mediastinum. What is the single most appropriate diagnostic test to establish the cause of his lymphadenopathy?