A 49-year-old woman presents with 6 months of symmetrical swelling and pain in the small joints of her hands and wrists, morning stiffness lasting ove...

Question

A 49-year-old woman presents with 6 months of symmetrical swelling and pain in the small joints of her hands and wrists, morning stiffness lasting over an hour and elevated inflammatory markers. Rheumatoid factor and anti-CCP antibodies are positive. What is the most appropriate initial disease-modifying pharmacological treatment?

Accepted Answer

Methotrexate with folic acid supplementation

Answer

Paracetamol as required only

Answer

Short course of oral prednisolone without further therapy

Answer

Allopurinol 100 mg daily

Answer

Colchicine 0.5 mg twice daily long term

au-amc MCQ (SBA): Rheumatoid arthritis initial DMARD