A 45-year-old man with obesity and metabolic syndrome is found to have persistently elevated ALT and ultrasound evidence of fatty infiltration of the ...

Question

A 45-year-old man with obesity and metabolic syndrome is found to have persistently elevated ALT and ultrasound evidence of fatty infiltration of the liver. Viral hepatitis serologies are negative and alcohol intake is minimal. What is the most important initial management strategy?

Accepted Answer

Lifestyle modification with weight loss and management of metabolic risk factors

Answer

Start long-term corticosteroids

Answer

Begin high-dose vitamin E in all patients

Answer

Start antiviral therapy

Answer

Immediate liver transplantation assessment

ca-mccqe1 MCQ (SBA): Non-alcoholic fatty liver disease

A 45-year-old man with obesity and metabolic syndrome is found to have persistently elevated ALT and ultrasound evidence of fatty infiltration of the liver. Viral hepatitis serologies are negative and alcohol intake is minimal. What is the most important initial management strategy?