Question

A 52-year-old woman is admitted with febrile neutropenia (ANC 0.3 × 10⁹/L) following chemotherapy for breast cancer. According to Canadian and international guidelines, what is the most appropriate empiric therapy?

Accepted Answer

Intravenous broad-spectrum antipseudomonal beta-lactam

Answer

Oral amoxicillin alone

Answer

No antibiotics until cultures are positive

Answer

Oral macrolide plus doxycycline

Answer

High-dose steroids alone

Practice question

A 52-year-old woman is admitted with febrile neutropenia (ANC 0.3 × 10⁹/L) following chemotherapy for breast cancer. According to Canadian and international guidelines, what is the most appropriate empiric therapy?