A 29-year-old man presents with polyuria, polydipsia and weight loss over 6 weeks. Random plasma glucose is 17.5 mmol/L and ketones are present in uri...

Question

A 29-year-old man presents with polyuria, polydipsia and weight loss over 6 weeks. Random plasma glucose is 17.5 mmol/L and ketones are present in urine. Arterial pH is 7.29, bicarbonate 16 mmol/L and serum ketones are elevated. According to Diabetes Canada, what is the most appropriate initial treatment?

Accepted Answer

Admit and start intravenous insulin infusion with intravenous fluids and electrolyte monitoring

Answer

Start metformin orally and review in 1 week

Answer

Start basal insulin once daily as outpatient

Answer

Start SGLT2 inhibitor therapy as an outpatient

Answer

Treat with oral sulfonylurea

ca-mccqe1 MCQ (SBA): Diabetic ketoacidosis