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MediumPsychiatryMajor depressive disorderau-amcau-racgp

A 40-year-old woman presents with low mood, anhedonia, poor concentration and early morning wakening for 6 weeks. She has no past psychiatric history, no substance misuse and denies suicidality. She continues to work but with significant difficulty. According to Australian depression guidelines, what is the most appropriate initial management in general practice?

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