Question

A 45-year-old man with latent tuberculosis infection (positive interferon-gamma release assay, normal chest X-ray) is otherwise healthy. What is the most appropriate treatment to reduce risk of active TB?

Accepted Answer

Isoniazid-based preventive therapy for several months

Answer

No treatment is required

Answer

Empiric multi-drug TB therapy for 6 months

Answer

Routine annual chest X-ray only

Answer

Short course of systemic steroids

Practice question

A 45-year-old man with latent tuberculosis infection (positive interferon-gamma release assay, normal chest X-ray) is otherwise healthy. What is the most appropriate treatment to reduce risk of active TB?