A 27-year-old woman presents with fever, widespread targetoid rash, mucosal erosions and ocular involvement after starting lamotrigine 2 weeks ago. Sh...

Question

A 27-year-old woman presents with fever, widespread targetoid rash, mucosal erosions and ocular involvement after starting lamotrigine 2 weeks ago. She is systemically unwell. What is the most appropriate management?

Accepted Answer

Immediate cessation of lamotrigine and transfer to a burns or high-dependency unit

Answer

Continue lamotrigine and add topical steroids

Answer

Treat with oral antihistamines alone

Answer

Discharge with reassurance that this is a mild drug rash

Answer

Start another antiepileptic from the same class immediately

au-acem MCQ (SBA): Stevens-Johnson syndrome management

A 27-year-old woman presents with fever, widespread targetoid rash, mucosal erosions and ocular involvement after starting lamotrigine 2 weeks ago. She is systemically unwell. What is the most appropriate management?