Question

A 79-year-old woman on long-term warfarin for atrial fibrillation presents with a large intracerebral haemorrhage and INR 3.5. What is the most appropriate strategy for rapid anticoagulation reversal?

Accepted Answer

IV vitamin K and four-factor prothrombin complex concentrate

Answer

Stop warfarin only and observe

Answer

Oral vitamin K alone

Answer

Fresh frozen plasma only

Answer

No reversal as AF requires continuous anticoagulation

Practice question

A 79-year-old woman on long-term warfarin for atrial fibrillation presents with a large intracerebral haemorrhage and INR 3.5. What is the most appropriate strategy for rapid anticoagulation reversal?