Question

A 50-year-old man presents with polyuria, polydipsia and nocturia. IPSS suggests severe lower urinary tract symptoms and PSA is markedly elevated. Digital rectal exam shows a hard, irregular prostate. What is the most appropriate next investigation?

Accepted Answer

Urgent referral for prostate biopsy and imaging

Answer

Start alpha-blocker and no further investigations

Answer

Repeat PSA in 2 years

Answer

Urinalysis only

Answer

Abdominal ultrasound only

Practice question

A 50-year-old man presents with polyuria, polydipsia and nocturia. IPSS suggests severe lower urinary tract symptoms and PSA is markedly elevated. Digital rectal exam shows a hard, irregular prostate. What is the most appropriate next investigation?