A 50-year-old woman presents with symmetrical swelling and tenderness of the metacarpophalangeal and proximal interphalangeal joints for 3 months, mor...

Question

A 50-year-old woman presents with symmetrical swelling and tenderness of the metacarpophalangeal and proximal interphalangeal joints for 3 months, morning stiffness lasting 90 minutes, and elevated inflammatory markers. Anti-CCP antibodies are positive. According to Canadian Rheumatology Association guidance, what is the preferred initial disease-modifying treatment?

Accepted Answer

Methotrexate as the anchor DMARD

Answer

Low-dose prednisone alone

Answer

Hydroxychloroquine monotherapy

Answer

Biologic TNF inhibitor as first-line monotherapy

Answer

Non-steroidal anti-inflammatory drugs alone

ca-mccqe1 MCQ (SBA): Rheumatoid arthritis