Question

A 59-year-old man with long-standing type 2 diabetes and hypertension has an eGFR of 52 mL/min/1.73 m² and a urine albumin-creatinine ratio of 60 mg/mmol. According to Diabetes Canada and nephrology guidance, which is the most appropriate renoprotective strategy?

Accepted Answer

Start or uptitrate an ACE inhibitor or ARB to maximum tolerated dose

Answer

Stop his ACE inhibitor to avoid further kidney damage

Answer

Use a thiazide diuretic alone for blood pressure control

Answer

Aim for a systolic blood pressure target above 150 mm Hg to preserve renal perfusion

Answer

Avoid SGLT2 inhibitors because of CKD

Practice question

A 59-year-old man with long-standing type 2 diabetes and hypertension has an eGFR of 52 mL/min/1.73 m² and a urine albumin-creatinine ratio of 60 mg/mmol. According to Diabetes Canada and nephrology guidance, which is the most appropriate renoprotective strategy?