Question

A 68-year-old man with type 2 diabetes has been taking metformin 1 g twice daily for several years. Recent blood tests show an eGFR of 28 mL/min/1.73 m², down from 40 mL/min/1.73 m² 6 months ago. He is otherwise stable. What is the most appropriate management of his metformin therapy?

Accepted Answer

Cease metformin due to reduced renal function

Answer

Continue metformin at the same dose

Answer

Increase metformin dose to improve glycaemic control

Answer

Reduce metformin to 500 mg daily but continue indefinitely

Answer

Switch metformin to a sulfonylurea without reviewing other factors

Practice question

A 68-year-old man with type 2 diabetes has been taking metformin 1 g twice daily for several years. Recent blood tests show an eGFR of 28 mL/min/1.73 m², down from 40 mL/min/1.73 m² 6 months ago. He is otherwise stable. What is the most appropriate management of his metformin therapy?