Question

A 50-year-old woman presents with new-onset fatigue, pruritus and right upper quadrant discomfort. Labs show cholestatic pattern: ALP markedly elevated, GGT elevated, AMA positive. According to Canadian hepatology practice, what is the most likely diagnosis?

Accepted Answer

Primary biliary cholangitis

Answer

Primary sclerosing cholangitis

Answer

Autoimmune hepatitis

Answer

Gallstone disease

Answer

Viral hepatitis B

Practice question

A 50-year-old woman presents with new-onset fatigue, pruritus and right upper quadrant discomfort. Labs show cholestatic pattern: ALP markedly elevated, GGT elevated, AMA positive. According to Canadian hepatology practice, what is the most likely diagnosis?