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MediumPsychiatryMajor depressive disorder first-line treatmentca-mccqe1ca-ccfp

A 42-year-old man presents with a 3-month history of low mood, anhedonia, poor concentration and early morning wakening. There are no psychotic features, and he denies suicidal ideation. He has no significant medical history. According to CANMAT guidelines, what is an appropriate first-line treatment approach for moderate major depressive disorder?

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