Question

A 64-year-old man with type 2 diabetes, prior myocardial infarction and eGFR 60 mL/min/1.73 m² has an HbA1c of 7.9% on maximally tolerated metformin. He is overweight and has no history of ketoacidosis. According to Diabetes Canada's cardiorenal risk guidance, what is the best next agent to add?

Accepted Answer

An SGLT2 inhibitor or GLP-1 receptor agonist with proven cardiovascular benefit

Answer

A sulfonylurea

Answer

A thiazolidinedione

Answer

A dipeptidyl peptidase-4 (DPP-4) inhibitor

Answer

Basal insulin

Practice question

A 64-year-old man with type 2 diabetes, prior myocardial infarction and eGFR 60 mL/min/1.73 m² has an HbA1c of 7.9% on maximally tolerated metformin. He is overweight and has no history of ketoacidosis. According to Diabetes Canada's cardiorenal risk guidance, what is the best next agent to add?