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MediumInfectious DiseasesSepsis and septic shockau-amcau-racpau-acem

A 70-year-old man presents to the emergency department with fever, hypotension, tachycardia and confusion. He has a suspected urinary source of sepsis. Lactate is elevated and blood pressure remains low after an initial 500 mL fluid bolus. What is the most appropriate next step in management?

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