A 34-year-old woman with relapsing-remitting multiple sclerosis presents with a relapse characterised by new right leg weakness and sensory changes fo...

Question

A 34-year-old woman with relapsing-remitting multiple sclerosis presents with a relapse characterised by new right leg weakness and sensory changes for 4 days. MRI shows enhancing demyelinating lesions. She has no evidence of infection. What is the most appropriate acute management?

Accepted Answer

High-dose IV methylprednisolone for 3-5 days

Answer

Start disease-modifying therapy only and observe the relapse

Answer

Oral prednisolone 5 mg daily

Answer

Immediate plasmapheresis alone

Answer

No treatment; most relapses recover completely without intervention

au-amc MCQ (SBA): Multiple sclerosis relapse

A 34-year-old woman with relapsing-remitting multiple sclerosis presents with a relapse characterised by new right leg weakness and sensory changes for 4 days. MRI shows enhancing demyelinating lesions. She has no evidence of infection. What is the most appropriate acute management?