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MediumRespiratoryAcute exacerbation of COPDau-amcau-racpau-acem

A 72-year-old man with known COPD (FEV1 40% predicted) presents with increased breathlessness, wheeze and purulent sputum for 3 days. He is afebrile, oxygen saturation is 91% on room air and chest X-ray shows no new consolidation. Which is the most appropriate initial management of this acute exacerbation in the emergency department?

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