Question

A 24-year-old woman presents 6 hours after ingesting 20 g of paracetamol in a suicide attempt. Serum paracetamol level at 4 hours lies above the nomogram treatment line. According to updated Australian guidelines, what is the recommended IV N-acetylcysteine regimen?

Accepted Answer

Two-bag regimen: 200 mg/kg over 4 hours then 100 mg/kg over 16 hours

Answer

Traditional three-bag regimen over 20 hours

Answer

Single-bag infusion over 4 hours

Answer

Oral N-acetylcysteine only

Answer

No treatment is required if she is asymptomatic

Practice question

A 24-year-old woman presents 6 hours after ingesting 20 g of paracetamol in a suicide attempt. Serum paracetamol level at 4 hours lies above the nomogram treatment line. According to updated Australian guidelines, what is the recommended IV N-acetylcysteine regimen?