A 64-year-old man presents to an urban emergency department 60 minutes after the sudden onset of crushing central chest pain radiating to his left arm. He is diaphoretic and nauseated. His ECG shows 3 mm ST elevation in leads II, III and aVF with reciprocal ST depression in aVL. The nearest percutaneous coronary intervention (PCI) centre is onsite and available. According to contemporary STEMI management principles in Canada, what is the most appropriate next step?