Question

A 35-year-old woman presents with chronic diarrhoea, weight loss and iron deficiency anaemia. Serology shows elevated tissue transglutaminase IgA. What is the most appropriate next step?

Accepted Answer

Small bowel biopsy via upper endoscopy to confirm diagnosis

Answer

Begin a gluten-free diet without further testing

Answer

Colonoscopic biopsy

Answer

Empiric steroids

Answer

Reassure that this is irritable bowel syndrome

Practice question

A 35-year-old woman presents with chronic diarrhoea, weight loss and iron deficiency anaemia. Serology shows elevated tissue transglutaminase IgA. What is the most appropriate next step?