A 52-year-old woman with long-standing poorly controlled hypertension and CKD presents with chronic low mood and loss of interest. She has moderate ma...

Question

A 52-year-old woman with long-standing poorly controlled hypertension and CKD presents with chronic low mood and loss of interest. She has moderate major depression. Which antidepressant would be a reasonable first-line pharmacological option consistent with RANZCP guidelines?

Accepted Answer

Sertraline

Answer

Diazepam

Answer

Amitriptyline at high dose as first-line

Answer

Perphenazine

Answer

Lithium

au-amc MCQ (SBA): Major depression pharmacotherapy

A 52-year-old woman with long-standing poorly controlled hypertension and CKD presents with chronic low mood and loss of interest. She has moderate major depression. Which antidepressant would be a reasonable first-line pharmacological option consistent with RANZCP guidelines?