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EasyNephrologyPre-renal acute kidney injuryca-mccqe1ca-rcpsc-im

A 70-year-old man presents with rising creatinine over several days following initiation of high-dose ibuprofen for osteoarthritis. His baseline creatinine was 90 µmol/L and is now 180 µmol/L. He is volume-depleted on examination, with low JVP and dry mucous membranes. Urinalysis is bland. What is the most likely diagnosis?

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